Evaluation of cardiovascular biomarkers in patients with age-related wet macular degeneration
نویسندگان
چکیده
منابع مشابه
Evaluation of cardiovascular biomarkers in patients with age-related wet macular degeneration
AIM To evaluate levels of homocysteine, asymmetric dimethylarginine (ADMA), and nitric oxide (NO), as well as activity of endothelial NO synthase (eNOS), in patients with age-related macular degeneration (AMD). METHODS The levels of homocysteine, ADMA, and NO and activity of eNOS in patients who were diagnosed with wet AMD by fundus fluorescein angiography (n=30) were compared to a control gr...
متن کاملWet Age Related Macular Degeneration
Age related macular degeneration (AMD) is the leading cause of blindness in the developed countries. Approximately 8 million people in America have AMD and the number of advanced AMD is likely to rise by 50% by year 2020 due to the projected increase in the number of elderly people (Friedman et al., 2004). AMD is a condition of significant morbidity in terms of both physical and mental health (...
متن کاملEvaluation of circulating miRNAs in wet age-related macular degeneration
PURPOSE In the present study, we aimed to investigate the changes in plasma miRNA in patients with wet age-related macular degeneration. METHODS The expression profiles of 384 miRNAs in plasma from 33 patients (22 male, 11 female) who were diagnosed with wet age-related macular degeneration with fundus examination, fundus fluorescein angiography, and optical coherence tomography and 31 contro...
متن کاملImaging of Wet Age-Related Macular Degeneration
All images are acquired on a Spectralis device from Heidelberg Engineering. Image courtesy of Dr. (med) Ke-nan Damer, Birmingham Midlands Eye Centre, Sandwell and West Birmingham NHS Trust. Fig. 1. a Shows the macula of a left eye with reduced foveal reflectivity on the infra-red picture, which is due to intra-retinal fluid caused by choroidal neovascularization (CNV) related to wet AMD. In b ,...
متن کاملAssociation of Apolipoprotein E Alleles with Susceptibility to Age-Related Macular Degeneration in Iranian Patients
Background: We aimed here to investigate the association between alleles and genotypes of APOE and Age-related macular degeneration (AMD) development. Materials and Methods: After ophthalmological examination, 120 patients with confirmed AMD and 120 healthy controls were enrolled in the study. The polymorphic segment of APOE gene was PCR-amplified and sequenced to determine the frequency distr...
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ژورنال
عنوان ژورنال: Clinical Ophthalmology
سال: 2014
ISSN: 1177-5483
DOI: 10.2147/opth.s66160